Journal
BRITISH JOURNAL OF NUTRITION
Volume 118, Issue 1, Pages 60-68Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0007114517001805
Keywords
Diabetes; Polyphenols; Flavonoids; Phenolic acids; Lignans; Stilbenes; Prospective studies
Categories
Funding
- Wellcome Trust [064947/Z/01/Z, 081081/Z/06/Z]
- US National Institute on Ageing [1R01 AG23522-01]
- MacArthur Foundation Initiative on Social Upheaval and Health [71208]
Ask authors/readers for more resources
This study aimed to test the association between dietary content of total and individual classes of polyphenols and incident cases of type 2 diabetes in Polish adults participating to the Health, Alcohol and Psychosocial factors In Eastern Europe study. At baseline, diet by 148-item FFQ and health information were collected from 5806 participants free of diabetes. Self-reported incident type 2 diabetes was ascertained at 2-4-year follow-up visit. OR and 95% CI of type 2 diabetes comparing the various categories of polyphenol intake to the lowest one (reference category) and as 1 SD increase modelled as continuous variable were calculated by performing age-, energy-, and multivariate-adjusted logistic regression models. During the follow-up, 456 incident cases of type 2 diabetes occurred. When comparing extreme quartiles, intake of total polyphenol was inversely associated with the risk of type 2 diabetes (OR 0.43; 95% CI 0.30, 0.61); 1 SD increase was associated with a reduced risk of diabetes (OR 0.68; 95% CI 0.59, 0.79). Among the main classes of polyphenols, flavonoids, phenolic acids, and stilbenes were independent contributors to this association. Both subclasses of phenolic acids were associated with decreased risk of type 2 diabetes, whereas among subclasses of flavonoids, high intake of flavanols, flavanones, flavones and anthocyanins was significantly associated with decreased risk of type 2 diabetes. Total dietary polyphenols and some classes of dietary polyphenols were associated with lower risk of type 2 diabetes.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available