Journal
CARBOHYDRATE POLYMERS
Volume 173, Issue -, Pages 547-555Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.carbpol.2017.06.036
Keywords
Biopolymers; Polyvinyl alcohol; Cellulose nanofibril; Porous hydrogel; Biocompatibility
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Funding
- Fundamental Research Funds for the Central Universities [30920130121001]
- National Natural Science Foundation of China [51272106, 21206076]
- Natural Science Foundation of Jiangsu Province [BK2012401]
- Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD, China)
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In this study, the reinforcing effects of cellulose nanofibrils (CNFs) on poly (vinyl alcohol) (PVA) matrix were explored. And ethylene glycol was used to enhance the water content and phosphate buffer saline (PBS) absorbency. The morphological aspects of the hydrogel were studied by transmission electron microscope (TEM) and scanning electron microscopy (SEM). The presence of interactions, changes in crystallinity as well as thermal behaviour were investigated by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) and thermogravimetry respectively. With the increase of CNFs concentration, the composite greatly improved its mechanical strength while maintaining remarkable ductility through tensile test results. The positive results of cell toxicity test suggested our porous hydrogel could provide ideal cell growth environment. This work revealed that CNFs hydrolysed by bacterial cellulose could perform as a perfect reinforcing agents which is of great interest in the fields of biotechnology and biomedicine with the potential values in cell culture, co-cultivation, as well as biomedical scaffold materials. (C) 2017 Elsevier Ltd. All rights reserved.
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