4.7 Article

A unique rectilinearly π-extended rhodamine dye with large Stokes shift and near-infrared fluorescence for bioimaging

Journal

CHEMICAL COMMUNICATIONS
Volume 53, Issue 77, Pages 10727-10730

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc06220f

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Funding

  1. National Natural Science Foundation of China [NNSFC21272172]
  2. Natural Science Foundation of Tianjin [12JCZDJC21000]

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The synthesis of a novel rectilinearly pi-extended rhodamine dye (TJ730) has been described. It exhibits NIR fluorescence emission with a Stokes shift of >110 nm. TJ730 and its ester derivative are cell permeable, have low cytotoxicity, are biocompatible, and can be directly used as NIR tracers for lysosome staining. Using TJ730 as a precursor, two probes have been prepared for Cu2+.

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