4.4 Review

Progress in C-N Bonds Formation Using t-BuONO

Journal

CHINESE JOURNAL OF ORGANIC CHEMISTRY
Volume 37, Issue 8, Pages 1916-1923

Publisher

SCIENCE PRESS
DOI: 10.6023/cjoc201703039

Keywords

tert-butyl nitrite; C-N bond; nitration

Funding

  1. Ningbo University [ZX2016000706]
  2. K. C. Wong Magna Fund in Ningbo University

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The formation of C-N bonds by nitration is a powerful strategy for organic synthesis. Recently, the remarkable progress has been made in synthesis of nitrogen compounds using tert-butyl nitrite as nitration reagent. The present protocol, with a mild reaction condition and an excellent region selectivity, provides a green and efficient approach to construct C-N bonds. This review will summarize the recent development in this area on the basis of different substrates systems.

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