4.7 Article

Real time detection of ESKAPE pathogens by a nitroreductase-triggered fluorescence turn-on probe

Journal

CHEMICAL COMMUNICATIONS
Volume 53, Issue 81, Pages 11177-11180

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc07050k

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Funding

  1. National Natural Science Foundation of China (NSFC) [21778077, 21502236]
  2. Sino-German research project [GZ 1271]
  3. Beijing Nova Program [Z16111000490000]

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The identification of bacterial pathogens is the critical first step in conquering infection diseases. A novel turn-on fluorescent probe for the selective sensing of nitroreductase (NTR) activity and its initial applications in rapid, real-time detection and identification of ESKAPE pathogens have been reported.

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