Journal
BMC BIOLOGY
Volume 15, Issue -, Pages -Publisher
BMC
DOI: 10.1186/s12915-017-0432-0
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-
Categories
Funding
- MRC funding [MC_UU_12018/6]
- Canadian Institutes of Health Research [MOP123405, MOP133660, FDN-143202]
- Intramural Research Program of the National Institutes of Health
- Howard Hughes Medical Institute
- Higher Education Funding Council for England
- Vladimir Horowitz and Wanda Toscanini Horowitz Endowment
- Medical Research Council [G0801878, M010767, P0010091]
- Francis Crick Institute from Cancer Research UK [FC001187]
- UK Medical Research Council [FC001187]
- Welcome Trust [FC001187]
- FWO (Fonds Wetenschappelijk Onderzoek) [V443616N]
- CIHR MOP [133549]
- Canada Research Chair in Mitochondrial Cell Biology
- Biotechnology and Biological Sciences Research Council [BB/P003818/1, 1495066] Funding Source: researchfish
- Medical Research Council [MR/M010767/1, G0801878, MC_UU_00012/6, 1215854, MC_UU_12018/6] Funding Source: researchfish
- BBSRC [BB/P003818/1] Funding Source: UKRI
- MRC [MC_UU_00012/6, G0801878, MR/M010767/1, MC_UU_12018/6] Funding Source: UKRI
- Grants-in-Aid for Scientific Research [17K18142] Funding Source: KAKEN
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Discoveries spanning several decades have pointed to vital membrane lipid trafficking pathways involving both vesicular and non-vesicular carriers. But the relative contributions for distinct membrane delivery pathways in cell growth and organelle biogenesis continue to be a puzzle. This is because lipids flow from many sources and across many paths via transport vesicles, non-vesicular transfer proteins, and dynamic interactions between organelles at membrane contact sites. This forum presents our latest understanding, appreciation, and queries regarding the lipid transport mechanisms necessary to drive membrane expansion during organelle biogenesis and cell growth.
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