Journal
CHEMISTRY OF HETEROCYCLIC COMPOUNDS
Volume 53, Issue 11, Pages 1261-1267Publisher
SPRINGER
DOI: 10.1007/s10593-018-2204-3
Keywords
3-amino-1,2,4-triazole; benzoxadiazocine; oxygen-bridged structure; Biginelli reaction; cascade reaction; microwave-assisted synthesis; multicomponent reaction; reaction mechanism
Categories
Funding
- Artvin Coruh University [BAP-2012.F19.02.24]
- Council of Higher Education of Turkey, Mevlana Exchange Program [MEV-2016-027]
Ask authors/readers for more resources
A microwave-assisted Biginelli-like three-component condensation using salicylic aldehyde derivatives, acetone, and 5-substituted 3-amino-1,2,4-triazoles instead of the urea component results in the formation of oxygen-bridged tetrahydrotriazolopyrimidine derivatives (11,12-dihydro-5,11-methano[1,2,4]triazolo[1,5-c][1,3,5]benzoxadiazocines) in good yields and high purity. A plausible reaction mechanism for this transformation is discussed in details using literature and experimental data.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available