4.6 Article

An Adjustable Multi-Scale Single Beam Acoustic Tweezers Based on Ultrahigh Frequency Ultrasonic Transducer

Journal

BIOTECHNOLOGY AND BIOENGINEERING
Volume 114, Issue 11, Pages 2637-2647

Publisher

WILEY
DOI: 10.1002/bit.26365

Keywords

acoustic trapping; ultrahigh frequency ultrasonic transducer; adjustable multi-scale tweezers; microparticle trapping and manipulation; piezoelectric actuator model

Funding

  1. Foundation for the National Institutes of Health [P41-EB002182]
  2. Hong Kong Research Grants Council [ECS 253001/14P]
  3. China Scholarship Council (CSC)

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This paper reports the fabrication, characterization, and microparticle manipulation capability of an adjustable multi-scale single beam acoustic tweezers (SBAT) that is capable of flexibly changing the size of tweezers like ordinary metal tweezers with a single-element ultrahigh frequency (UHF) ultrasonic transducer. The measured resonant frequency of the developed transducer at 526MHz is the highest frequency of piezoelectric single crystal based ultrasonic transducers ever reported. This focused UHF ultrasonic transducer exhibits a wide bandwidth (95.5% at -10dB) due to high attenuation of high-frequency ultrasound wave, which allows the SBAT effectively excite with a wide range of excitation frequency from 150 to 400MHz by using the piezoelectric actuator model. Through controlling the excitation frequency, the wavelength of ultrasound emitted from the SBAT can be changed to selectively manipulate a single microparticle of different sizes (3-100m) by using only one transducer. This concept of flexibly changing tweezers size is firstly introduced into the study of SBAT. At the same time, it was found that this incident ultrasound wavelength play an important role in lateral trapping and manipulation for microparticle of different sizes. (C) 2017 Wiley Periodicals, Inc.

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