Journal
THERAPEUTIC DELIVERY
Volume 8, Issue 11, Pages 957-966Publisher
FUTURE SCI LTD
DOI: 10.4155/tde-2017-0067
Keywords
3D printing; FDM; fused deposition modeling; HME; hot melt extrusion
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Funding
- National Council for the Research and Development (CNPq) of Brazilian Government
- Coordination for Higher Education Personnel Improvement (CAPES)
- Research support foundation of the Federal District (FAPDF)
- CAPES
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The production process of 3D-printed drugs offers unique advantages such as the possibility of individualizing the drug therapy and easily associating different drugs and release technologies in the same pharmaceutical unit. Fused deposition modeling, a 3D printing technique, seems especially interesting for pharmaceutical applications, due to its low cost, precise and reproducible control of the printed structures, and versatility for industrial and laboratory scale. This technique combined with another technology already adapted for the pharmaceutical industry, the hot melt extrusion, is able to incorporate various mechanisms of modified drug release. This special report aims to bring together data of the experimental progress achieved using the fused deposition modeling 3D printing combined with hot melt extrusion technique and its potential in drug delivery. [GRAPHICS]
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