Journal
BIOTECHNOLOGY AND BIOENGINEERING
Volume 114, Issue 11, Pages 2424-2431Publisher
WILEY
DOI: 10.1002/bit.26349
Keywords
craniofacial tissue; bioprinting; bone repair; regenerative medicine
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Funding
- National Science Foundation, Division of Civil, Mechanical and Manufacturing Innovation [1600118]
- Div Of Civil, Mechanical, & Manufact Inn
- Directorate For Engineering [1600118] Funding Source: National Science Foundation
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Craniofacial (CF) tissue is an architecturally complex tissue consisting of both bone and soft tissues with significant patient specific variations. Conditions of congenital abnormalities, tumor resection surgeries, and traumatic injuries of the CF skeleton can result in major deficits of bone tissue. Despite advances in surgical reconstruction techniques, management of CF osseous deficits remains a challenge. Due its inherent versatility, bioprinting offers a promising solution to address these issues. In this review, we present and analyze the current state of bioprinting of bone tissue and highlight how these techniques may be adapted to serve regenerative therapies for CF applications. (C) 2017 Wiley Periodicals, Inc.
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