Journal
VIRUS GENES
Volume 53, Issue 6, Pages 883-897Publisher
SPRINGER
DOI: 10.1007/s11262-017-1501-8
Keywords
Poxvirus; Orthopoxvirus; Yoka poxvirus; Zoonotic; Murmansk; Virus virulence; Complete genome
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Funding
- Natural Sciences and Engineering Research Council
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The genome sequence and annotation of two novel poxviruses, NY_014 and Murmansk, are presented. Despite being isolated on different continents and from different hosts, the viruses are relatively similar, albeit distinct species. The closest known relative of the novel viruses is Yoka poxvirus. Five novel genes were found in these genomes, two of which were MHC class I homologs. Although the core of these genomes was well conserved, the terminal regions showed significant variability with large deletions and surprising evidence of recombination with orthopoxviruses.
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