4.7 Review

Chitosan and its derivatives as vehicles for drug delivery

Journal

DRUG DELIVERY
Volume 24, Issue 2, Pages 108-113

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/10717544.2017.1399305

Keywords

Chitosan; derivatives; vehicles; sustained release; controlled release; targeted drug delivery

Funding

  1. Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry
  2. Chongqing Key Research Project of Basic Science & Frontier Technology [cstc2017jcyjBX0012]
  3. Scientific and Technological Research Program of Chongqing Municipal Education Commission [KJ1400523]
  4. Foundation Project of Chongqing Normal University [14XYY020]
  5. Chongqing General Research Project of Basic Science & Frontier Technology [cstc2015jcyjA10054]
  6. Chongqing Normal University Postgraduate's Research and Innovation Project [YKC17004]
  7. Open Foundation Project of University Engineering Research Center for Bioactive Substances in Chongqing [AS201614]
  8. Chongqing University Students' Training Project of Innovation & Undertaking, China [201610637076]

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Chitosan and its derivatives as vehicles for drug delivery can achieve the purpose of sustained release and controlled release for drugs, improve the stability of drugs, and reduce adverse drug reactions. So, the bioavailability of drugs can be enhanced. Therefore, chitosan and its derivatives have become a hotspot in the field of drug delivery. Their characteristics as drug delivery vectors were introduced, the types and applications were summarized. The development direction of chitosan and its derivatives in this field was also forecasted.

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