Journal
VETERINARY JOURNAL
Volume 220, Issue -, Pages 48-50Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.tvjl.2017.01.004
Keywords
Labrador retriever; Congenital malformation; Brachycephaly; X-linked inheritance
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Seven male Labrador retriever puppies from four different litters were identified with a brachycephalic-like face and skull, associated with low birth weight, severe growth retardation, and reduced abilities to crawl and suckle, which were not compatible with survival. Excessive doming of the cranium, brachygnathia superior and inferior, and an abnormally opened fontanelle were found in all affected puppies by computed tomography and at post-mortem examination. Pedigree analysis supported an X-linked recessive mode of inheritance. (C) 2017 Elsevier Ltd. All rights reserved.
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