Journal
CHEMISTRY-A EUROPEAN JOURNAL
Volume 23, Issue 58, Pages 14450-14453Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201704045
Keywords
arylation; C-H activation; metallaphotoredox; palladium; photoredox
Categories
Ask authors/readers for more resources
Herein we describe the auxiliary-directed arylation of unactivated C(sp(3))-H bonds with aryldiazonium salts, which proceeds under synergistic photoredox and palladium catalysis. The site-selective arylation of aliphatic amides with alpha-quaternary centres is achieved with high selectivity for beta-methyl C(sp(3))-H bonds. This operationally simple method is compatible with carbocyclic amides, a range of aryldiazonium salts and proceeds at ambient conditions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available