Journal
EUROPEAN HEART JOURNAL
Volume 37, Issue 10, Pages 840-848Publisher
OXFORD UNIV PRESS
DOI: 10.1093/eurheartj/ehv650
Keywords
Endocarditis; Guidelines; Valvular surgery
Categories
Funding
- French Ministry of Health
- Societe Francaise de Cardiologie
- European Society of Clinical Microbiology and Infectious Diseases
- Novartis Laboratories
- French Ministry of Health
- Societe Francaise de Cardiologie
- European Society of Clinical Microbiology and Infectious Diseases
- Novartis Laboratories
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Aims Indications for surgery in acute infective endocarditis (IE) are detailed in guidelines, but their application is not well known. We analysed the agreement between the patient's attending physicians and European Society of Cardiology guidelines regarding indications for surgery. We also assessed whether surgery was performed in patients who had an indication. Methods and results From the 2008 prospective population-based French survey on IE, 303 patients with definite left-sided native IE were identified. For each case, we prospectively recorded (i) indication for surgery according to the attending physicians and (ii) indication for surgery according to guidelines. Surgery was indicated in 194 (65%) patients according to attending physicians and in 221 (73%) according to guidelines, while 139 (46%) underwent surgery. Agreement was moderate between attending physicians and guidelines (kappa 0.41-0.59) and between indication according to guidelines and the performance of surgery (kappa 0.38). Of the 90 (30%) patients not operated despite indication, contraindication to surgery was reported by the attending physicians in 42 (47%), and indication was not identified in 48 (53%). One-year survival was 76% in patients with indication and surgery performed (n = 131), 69% in patients without indication and no surgery (n = 74), 56% in patients with identified indication and contraindication to surgery (n = 42), and 60% in patients with no identified indication (n = 48; P = 0.059). Conclusion Cardiac surgery during acute IE was recommended in almost three out of four patients, although fewer than half were actually operated. Indication was not acknowledged by the attending physicians in one out of six patients.
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