4.7 Article

A NIR phosphorescent osmium(II) complex as a lysosome tracking reagent and photodynamic therapeutic agent

Journal

CHEMICAL COMMUNICATIONS
Volume 53, Issue 91, Pages 12341-12344

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc07776a

Keywords

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Funding

  1. National Natural Science Foundation of China (NSFC) [21701113]
  2. Science and Technology Foundation of Shenzhen [JCYJ20170302144346218]
  3. NSFC [21471164, 21525105, 21374064, 21471101, 21671137]
  4. 973 program [2015CB856301]
  5. Foundation for Emerging Industries of Strategic Importance of Shenzhen [JCY20150324140036843]

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A novel near infrared (NIR) phosphorescent osmium complex (Os1) was developed for lysosome tracking and photodynamic therapy. Owing to its NIR photophysical properties, cellular imaging ability and phototoxicity, it has advantages over its ruthenium analogue (Ru1).

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