The choice of ultrasound assisted extraction coupled with spectrophotometric for rapid determination of gallic acid in water samples: Central composite design for optimization of process variables

A sensitive procedure namely ultrasound-assisted (UA) coupled dispersive nano solid-phase microextraction spectrophotometry (DNSPME-UV-Vis) was designed for preconcentration and subsequent determination of gallic acid (GA) from water samples, while the detailed of composition and morphology and also purity and structure of this new sorbent was identified by techniques like field emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD) and Energy-dispersive X-ray spectroscopy (EDX) techniques. Among conventional parameters viz. pH, amount of sorbent, sonication time and volume of elution solvent based on Response Surface Methodology (RSM) and central composite design according to statistics based contour the best operational conditions was set at pH of 2.0; 1.5 mg sorbent, 4.0 min sonication and 150 mu L ethanol. Under these pre-qualified conditions the method has linear response over wide concentration range of 15-6000 ng mL(-1) with a correlation coefficient of 0.9996. The good figure of merits like acceptable LOD (S/N = 3) and LOQ (S/N = 10) with numerical value of 2.923 and 9.744 ng mL(-1), respectively and relative recovery between 95.54 and 100.02% show the applicability and efficiency of this method for real samples analysis with RSD5 below 6.0%. Finally the method with good performance were used for monitoring under study analyte in various real samples like tap, river and mineral waters. (C) 2016 Elsevier B.V. All rights reserved.