Journal
DATA IN BRIEF
Volume 15, Issue -, Pages 824-827Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.dib.2017.10.058
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Funding
- SVSE5 program, ATHERANOS [ANR-13-BSV5-0018]
- French Ministry of Education Research and Technology
- Agence Nationale de la Recherche (ANR) [ANR-13-BSV5-0018] Funding Source: Agence Nationale de la Recherche (ANR)
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This article present data related to the publication entitled Iron oxide core oil-in-water nanoemulsion as tracer for atherosclerosis MPI and MRI imaging (Prevot et al., 2017) [1]. Herein we describe the engineering in the baculovirus-insect cell system and purification processes of the human scFv-Fc TEG4-2C antibody, specific of platelets within the atheroma plaque. For molecular targeting purpose, atheroma specific antibody was conjugated to nanoemulsions (NEs) using a heterobifunctional linker (DSPE-PEG-maleimide). Atheroma labelling was assayed by immunochemistry on arterial sections from rabbits. (C) 2017 Published by Elsevier Inc.
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