Journal
TRENDS IN PARASITOLOGY
Volume 33, Issue 7, Pages 519-531Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.pt.2017.04.001
Keywords
-
Categories
Funding
- State University of New York
- NIH [AI124677, AI069986, NS072298]
Ask authors/readers for more resources
Toxoplasma gondii is a widespread parasitic pathogen that infects over a third of the world's population. Following an acute infection, the parasite can persist within its mammalian host as intraneuronal or intramuscular cysts. Cysts will occasionally reactivate, and - depending on the host's immune status and site of reactivation - encephalitis or myositis can develop. Because these diseases have high levels of morbidity and can be lethal, it is important to understand how Toxoplasma traffics to these tissues, how the immune response controls parasite burden and contributes to tissue damage, and what mechanisms underlie neurological and muscular pathologies that toxoplasmosis patients present with. This review aims to summarize recent important developments addressing these critical topics.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available