Journal
TRENDS IN FOOD SCIENCE & TECHNOLOGY
Volume 66, Issue -, Pages 135-145Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tifs.2017.06.008
Keywords
Oligosaccharides; Functional properties; Structural analysis; Milk oligosaccharides; Chemo-enzymatic synthesis
Categories
Funding
- National Natural Science Foundation of China [2016J06009]
- Science and Technology Major Project of Fujian Province, China [2014NZ0002-1]
- FAFU [KXb16011A, 612014042]
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Oligosaccharides offer beneficial effects on immune system and gut health, such as anticancer activity, immunomodulatory activity, and complement activation. Functional oligosaccharides are widely found in plants, algae, bacteria and higher fungi. Milk oligosaccharides, especially human milk oligosaccharides, have considerable health benefits, such as the growth-promotion of the beneficial bacterial flora in the intestines, and developing resistance to bactertial and viral infections. Recent developments in high performance liquid chromatography, mass spectrometry, nuclear magnetic resonance and capillary electrophoresis techniques contribute to the analysis of the oligosaccharide identification and mixture quantification. Synthesis of oligosaccharides is becoming increasingly important to pharmaceutical industries, in which chemo-enzymatic synthesis is considered as an effective method. This article gives a brief summary of structures, accessible sources, physiological and chemical characteristics, and potential health benefits of functional oligosaccharides. (C) 2017 Elsevier Ltd. All rights reserved.
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