Journal
CHEMICAL COMMUNICATIONS
Volume 53, Issue 95, Pages 12822-12825Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc07845e
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Funding
- EPSRC
- University of Bath
- Royal Society
- National Natural Science Foundation of China [21722801, 21572058]
- Science and Technology Commission of Shanghai Municipality [15540723800]
- Fundamental Research Funds for the Central Universities [222201717003]
- Shanghai Rising-Star Program [16QA1401400]
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Two boronate fluorescent probes have been developed for the detection of peroxynitrite (TCFB1 and TCFB2). TCFB1 was shown to have a low sensitvity towards peroxynitrite and have a poor solubility in aqueous solution whereas TCFB2 demonstrated high sensitivity towards peroxynitrite and mitochondria localisation with the ability to detect exogenous and endogenous peroxynitrite in live cells (Hep-G2, RAW 264.7, HeLa and A459).
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