4.8 Article

Clinical Implications of Single-Cell Microfluidic Devices for Hematological Disorders

Journal

ANALYTICAL CHEMISTRY
Volume 89, Issue 22, Pages 11881-11892

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.analchem.7b01013

Keywords

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Funding

  1. NIH NRSA [4T32HL116271-04]
  2. NIH [HL121264, HL130918, HL112309]
  3. NSF CAREER [1150235]
  4. DoD U.S. Army Medical Research and Material Command [W81XWH-13-1-0495]
  5. Children's Healthcare of Atlanta's Center for Pediatric Nano-medicine
  6. National Science Foundation [ECCS-1542174]

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Single-cell microfluidic devices are poised to substantially impact the hematology field by providing a high-throughput and rapid device to analyze disease-mediated biophysical cellular changes in the clinical setting in order to diagnose patients and monitor disease prognosis. In this Feature, we cover recent advances of single-cell microfluidic devices for studying and diagnosing hematological dysfunctions and the clinical impact made possible by these advances.

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