4.7 Review

Recent developments and trends in the application of strontium and its isotopes in biological related fields

Journal

TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume 90, Issue -, Pages 45-61

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2017.02.005

Keywords

Strontium; Isotope ratio; Biological marker; Medicine; Food authentication; Dietary habits; Migration pattern; Forensic science; MC ICP-MS; TIMS

Funding

  1. European Union's Horizon research and innovation programme [739568]
  2. Fundacao para a Ciencia e a Tecnologia (FCT), Portugal [UID/QUI/00100/2013]

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Strontium is a chemical element without biological functions in humans. In fact, only two biological roles are known, both as a biomineral constituent. However, strontium and calcium (a significant biometal) present chemical similarities; hence, the absorption of the former by living organisms is plausible. Based on the particular properties of isotopes of strontium several applications of this chemical element in biological sciences have been developed. These include its radioactive and non-radioactive isotopes in medical applications or resorting to its stable isotopes as analytical tools in isotope fingerprinting (Sr-87/Sr-86) to study dietary habits and migration patterns of ancient populations, food authentication and forensic sciences. This article, reviews papers published between 2012 and 2016, highlights the use of strontium isotope ratios for such biological related applications and compiles an analytical database, providing a valuable tool for future studies in the area. (C) 2017 Elsevier B.V. All rights reserved.

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