Journal
TOXIN REVIEWS
Volume 36, Issue 3, Pages 204-209Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/15569543.2017.1294605
Keywords
Ephestia kuehniella; oral toxicity; Carum copticum; thymol; detoxifying enzymes; intermediary metabolism
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The effects of Carum copticum essential oil (CC EO) and thymol were assayed against fourth instar of Ephestia kuehniella Zeller by determining insecticidal activities and enzymatic responses. Concentrations of 5.42 and 6.81l/ml were obtained as LC50 values for CC EO and thymol, respectively. The activities of esterases, aminotransferases, aldolase, and lactate dehydrogenase significantly decreased in the treated larvae by CC EO and thymol. Significant increases in glutathione S-transferases, -glutamyl transferase, and phosphatases were observed after treatment. Results revealed that CC EO and thymol significantly influenced the enzymatic activities of E. kuehniella leading to disruption of survival and metabolic responses.
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