Journal
CURRENT OPINION IN GENETICS & DEVELOPMENT
Volume 47, Issue -, Pages 17-23Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.gde.2017.07.014
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Funding
- National Institutes of Health [R01GM074737]
- Fonds de Recherche du Quebec - Sante
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Genome stability ensures individual fitness and reliable transmission of genetic information. Hybridization between diverging lineages can trigger genome instability, highlighting its potential role in post-zygotic reproductive isolation. We argue that genome instability is not merely one of several types of hybrid incompatibility, but rather that genome stability is one of the very first and most fundamental traits that can break down when two diverged genomes are combined. Future work will reveal how frequent and predictable genome instability is in hybrids, how it affects hybrid fitness, and whether it is a direct cause or consequence of speciation.
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