Journal
CHEMICAL REVIEWS
Volume 117, Issue 24, Pages 14015-14041Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.chemrev.7b00522
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Funding
- EPSRC Platform Grant Nanostructured Materials for Healthcare [EP/L020599/1]
- EPSRC [EP/L020599/1] Funding Source: UKRI
- Engineering and Physical Sciences Research Council [EP/L020599/1] Funding Source: researchfish
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This review is aimed to provide a concise yet extensive survey of key short bioactive peptide sequences for a range of applications ranging from biomaterials development to peptides with therapeutic uses. The following are considered: cell adhesion motifs, structural peptides, cell-penetrating and tumor-homing peptides, antimicrobial peptides, peptide hormones, growth factors and matrix metalloprotease substrates, neuropeptides, amyloid peptides, antioxidant peptides, peptide affinity tags, anticancer peptides, and others. This review provides a convenient resource, summarizing a broad range of important sequences with great utility as a resource concerning both small peptide drugs and also novel biofunctional peptide-based materials.
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