4.4 Article

First total synthesis of Pestalotioprolide C and its C7 epimer

Journal

TETRAHEDRON LETTERS
Volume 58, Issue 12, Pages 1198-1201

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2017.02.019

Keywords

Pestalotioprolide C; Total synthesis; Noyori asymmetric reduction; HWE olefination; Macrolactonization

Funding

  1. CSIR, New Delhi, India
  2. CSIR, New Delhi, India [CSC 0108]

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The first total synthesis of Pestalotioprolide C and C7-epi-Pestalotioprolide C adopting Noyori asymmetric reduction, HWE Olefination and Shiina macrolactonization as the key steps has been described. (C) 2017 Elsevier Ltd. All rights reserved.

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