Journal
TETRAHEDRON LETTERS
Volume 58, Issue 37, Pages 3654-3657Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2017.08.016
Keywords
Hg2+ recognition; Dithioacetal; ESIPT; AIE; Fluorescent probe; Cell imaging
Categories
Funding
- National Natural Science Foundation of China [21476029, U1608222]
- Program for Liaoning Excellent Talents in University [LR2015001, LJQ2014125]
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A new benzothizole-based fluorescent probe 1 for Hg2+ recognition utilizing ESIPT+AIE strategy has been developed. In THE/H2O (1:1, v/v, PBS 20 mM, pH = 8.5) mixed solution, probe 1 displays rapid fluorescence responses to Hg2+ ions with high selectivity and sensitivity through Hg2+-triggered releasing of a compound possessing ESIPT+AIE characteristics. Cell imaging investigations indicate that probe I is cell permeable with low toxicity to MCF-7 cells, and applicable to detect Hg2+ ions in living MCF-7 cells. (C) 2017 Elsevier Ltd. All rights reserved.
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