4.4 Article

Visible light mediated photocatalytic oxidative coupling reaction of N-phenyl tetrahydroisoquinoline with β-keto acids

Journal

TETRAHEDRON LETTERS
Volume 58, Issue 16, Pages 1592-1594

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2017.03.026

Keywords

Oxidative coupling reaction; Photocatalysis; Radical reaction; Tetrahydroisoquinolines

Funding

  1. Soonchunhyang University Research Fund
  2. Basic Science Research Program through the National Research Foundation of Korea [NRF-2014R1A2A01006224, 2016R1D1A1B03933723]
  3. National Research Foundation of Korea [2016R1D1A1B03933723] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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A visible light mediated photocatalytic oxidative coupling reaction of N-phenyl tetrahydroisoquinoline with beta-keto acids has been developed. This approach provides a mild and operationally simple access to the synthesis of C1-acylmethylated tetrahydroisoquinolines. (C) 2017 Elsevier Ltd. All rights reserved.

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