4.4 Article

Rapid aerobic iodination of arenes mediated by hypervalent iodine in fluorinated solvents

Journal

TETRAHEDRON LETTERS
Volume 58, Issue 7, Pages 645-648

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2017.01.003

Keywords

Aromatic substitution; Hypervalent compounds; Iodination; Fluorinated solvents

Funding

  1. Fulbright Scholar Program - USA [48131678]
  2. Slovenian Research Agency - Slovenia [P1-0134, BI-US/15-16-083]
  3. Slovene Human Resources Development and Scholarship Fund - Slovenia

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Arenes are rapidly converted to the corresponding iodides by aerobic oxidative iodination at room temperature by treatment with iodine and catalytic quantities of nitrous acid in a fluorinated solvent. Dichloroiodic acid is proposed as the actual iodination reagent. (C) 2017 Elsevier Ltd. All rights reserved.

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