4.4 Article

Direct C-H substitution reaction of anilides using hypervalent iodine and their regioselective issues

Journal

TETRAHEDRON LETTERS
Volume 58, Issue 41, Pages 3936-3938

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2017.08.079

Keywords

Hypervalent iodine; Anilide substitution; Regioselective reaction

Funding

  1. Naito Foundation

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The direct C-H substitution reactions of anilides using hypervalent iodine proceeded to afford azide, chloro, bromo, and fluoro derivatives, and their regioselectivity were described. In the specific reaction conditions, the unique regioisomers were obtained. (C) 2017 Elsevier Ltd. All rights reserved.

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