Journal
TETRAHEDRON LETTERS
Volume 58, Issue 18, Pages 1775-1777Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2017.03.072
Keywords
Total synthesis; Salprzelactone; Aldol reaction; Natural product; Enantioselective
Categories
Funding
- National Natural Science Foundation of China [21572089, 21302078, 21472072]
- Program for Changjiang Scholars and Innovative Research Team in University [PCSIRT: IRT_15R28]
- Fundamental Research Funds for the Central Universities [lzujbky-2016-52, lzujbky-2016-ct02]
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The first enantioselective total synthesis of (-)-salprzelactone, a seco-norabietane diterpenoid has been accomplished in only three steps. Key transformations of the synthesis include an intermolecular aldol reaction and lactonization. (C) 2017 Elsevier Ltd. All rights reserved.
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