Journal
TETRAHEDRON LETTERS
Volume 58, Issue 25, Pages 2433-2437Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2017.05.019
Keywords
Isocoumarins; Copper catalysis; Terminal alkynes; 2-Bromobenzoic esters
Categories
Funding
- National NSF of China [21573065, 21172062, 21273066]
- NSF of Hunan Province [2016JJ1007]
Ask authors/readers for more resources
An efficient method for the synthesis of 3-substituted isocoumarins that are an important class of biologically active scaffolds via annulation of 2-bromobenzoic esters with terminal alkynes by copper catalyzed is described. The advantages of this method include mild reaction conditions, high yield and regioselectivity, and wide tolerance toward functional groups. (C) 2017 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
