Journal
TETRAHEDRON LETTERS
Volume 58, Issue 27, Pages 2636-2639Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2017.05.051
Keywords
Carbamoylsilane; Aminocarbonylation reaction; Aminocarbonyl oxindole; One-pot synthesis
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Funding
- Shanxi Normal University of China [2R1516050602080102]
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The first addition reaction between isatins and carbamoysilane has been developed which provides 3hydroxy-3-aminocarbonyl-2-oxindoles core structures with excellent yields. Moreover, the reaction could undergo a one-pot synthesis process to furnish 3-hydroxy-3-aminocarbonyl-2-oxindole with gram-scale. (C) 2017 Elsevier Ltd. All rights reserved.
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