4.4 Article

[Cu(maloNHC)]-catalyzed synthesis of 2-aryl pyrazolo[5,1-a]isoquinolines by annulation of N′-(2-((trimethylsilyflethynyl)benzylidene)hydrazides with terminal aromatic alkynes

Journal

TETRAHEDRON
Volume 73, Issue 45, Pages 6428-6435

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2017.09.037

Keywords

Annulation; Alkynes; Pyrazolo[5,1-a]isoquinolines; N-heterocyclic carbene

Funding

  1. National Natural Science Foundation of China [21473097, 21673124]
  2. China Scholarship Council (CSC) [201506210176]

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A [Cu(maioNHC)]-catalyzed synthesis of 2-aryl pyrazolo[5,1-a]isoquinolines via annulation of N'-(2((trimethylsilyl)ethynyl)benzylidene)hydrazides with terminal aromatic alkynes was developed. (C) 2017 Elsevier Ltd. All rights reserved.

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