Journal
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY
Volume 31, Issue 2, Pages 218-242Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.berh.2017.11.007
Keywords
Sarcopenia; Muscle; Strength; Function; Ageing
Categories
Funding
- Medical Research Council
- National Institute of Health Research
- University of Southampton
- MRC [MC_U147585819, G0400491, MC_U147585827, MC_UP_A620_1015, MC_UU_12011/2] Funding Source: UKRI
- Medical Research Council [MC_UU_12011/1, MC_UU_12011/2, U1475000002, MC_UP_A620_1014, MC_U147585827, MC_U147585824, G0400491, MC_U147585819, U1475000001, MC_UP_A620_1015] Funding Source: researchfish
- National Institute for Health Research [NF-SI-0513-10085, NF-SI-0508-10082, ACF-2016-26-010] Funding Source: researchfish
- Versus Arthritis [19583] Funding Source: researchfish
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Sarcopenia is a condition that is characterized by loss of muscle mass, muscle strength and muscle functional impairment with ageing. The definition of sarcopenia has been through various permutations; however, an enormous recent breakthrough is the inclusion of the condition in the ICD-10 classification of diseases. This chapter covers the background issues regarding definition before describing the epidemiology of the disease according to human and environmental factors. It then provides a practical guide for the assessment of sarcopenia in a clinical setting and finishes with advice on present treatment and the exciting frontiers of future therapies. (C) 2017 Elsevier Ltd. All rights reserved.
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