Journal
KOREAN JOURNAL OF FAMILY MEDICINE
Volume 38, Issue 5, Pages 307-310Publisher
KOREAN ACAD FAMILY MEDICINE
DOI: 10.4082/kjfm.2017.38.5.307
Keywords
Amoxicillin-Clavulanic Acid; Hepatitis; Hepatology; Drug Reactions; Jaundice; Pruritus
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Amoxicillin-Clavulanic acid continues to be one of the most commonly used antibiotic combinations. Hepatic injury due to this antibiotic is rare. We report a case of amoxicillin-clavulanic acid induced hepatitis causing painless jaundice to bring to attention this rare side effect of this commonly used antibiotic. This is a case of a 62-year-old Caucasian female, who presented with acute onset severe painless jaundice, nausea, vomiting, and pruritus of less than 1-week duration. She had completed a course of amoxicillin-clavulanic acid 3 weeks prior to presentation. A careful history pointed to this simple diagnosis. It may be easily missed without an in-depth history and the patient may be subjected to unnecessary expensive tests. This case is reported to highlight cost conscious care by keeping in mind a rare side effect of the commonly used antibiotic.
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