4.3 Article

Green approach for the synthesis of 4-coumarin-4H-pyrans from 4-formylcoumarins and their antibacterial study

Journal

SYNTHETIC COMMUNICATIONS
Volume 47, Issue 17, Pages 1570-1576

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/00397911.2017.1336557

Keywords

4-Formylcoumarin; eco-friendly; malononitrile; triethylamine

Funding

  1. UGC
  2. DST, New Delhi

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A series of 4H-pyranocoumarin derivatives have been successfully synthesized under eco-friendly condition using triethylamine as a catalyst in short reaction time with excellent yield at room temperature. All the synthesized compounds were characterized by spectral analysis and screened for their antibacterial activity against Escherichia coli and Staphylococcus aureus, the results are quite promising.

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