4.3 Review

Synthetic strategies toward the synthesis of polyphenolic natural products: Pauciflorol F and isopaucifloral F: A review

Journal

SYNTHETIC COMMUNICATIONS
Volume 47, Issue 12, Pages 1121-1135

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/00397911.2017.1303510

Keywords

Drug discovery; indanones; isopaucifloral F; pauciflorol F; resveratrol

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Pauciflorol F and isopaucifloral F are very important polyphenolic natural products and exhibit a variety of biological activities such as antibiotic, anticancer, anti-HIV, antioxidant, antifungal, and anti-inflammatory activities. These important molecules have gained significant attraction of medicinal chemists and several new strategies have been developed toward the synthesis of pauciflorol F and isopaucifloral F. This review article summarizes the major synthetic approaches adopted for the synthesis of these two indanone-based compounds.

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