Journal
SYNTHESIS-STUTTGART
Volume 49, Issue 14, Pages 3171-3182Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0036-1588995
Keywords
tetrahydroquinolines; chromenes; nitrostyrenes; alkylation; electrophilic substitution; Friedel-Crafts reaction
Categories
Funding
- CSIR-India
- CSIR-India [CSC-0108]
Ask authors/readers for more resources
A simple and novel method has been developed for the C6-functionalization of unprotected tetrahydroquinoline with chromenes or beta-nitrostyrenes in aqueous medium to afford novel 6-substituted tetrahydroquinolines. This method is simple and convenient, and has low costs and mild reaction conditions. Regioselectively C6-alkylated products were obtained exclusively from tetrahydroquinoline, without the formation of C5-, C7-, C8-, or N-alkylated products.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available