Journal
SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA
Volume 26, Issue 2, Pages 257-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.soc.2016.10.006
Keywords
Esophageal cancer; Radiation; Chemotherapy; IMRT; Dose-escalation
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The treatment of locally advanced esophageal cancer is controversial. For patients who are candidates for surgical resection, multiple prospective clinical trials have demonstrated the advantages of neoadjuvant chemoradiation. For patients who are medically inoperable, definitive chemoradiation is an alternative approach with survival rates comparable to trimodality therapy. Although trials of dose escalation are ongoing, the standard radiation dose remains 50.4 Gy. Modern radiotherapy techniques such as
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