Journal
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS EXTRA
Volume 7, Issue 3, Pages 419-429Publisher
KARGER
DOI: 10.1159/000484137
Keywords
Alzheimer's disease; Anomia; Conceptual knowledge; Lexical retrieval; Semantic layer; Phonological layer
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Funding
- Isfahan University of Medical Sciences [395249]
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Background: The purpose of the study was to analyze naming errors in patients with Alzheimer's disease in comparison to healthy subjects and determine the underlying cause of naming errors in these patients. Method: In this study, we included 35 healthy elderly subjects, 23 patients with mild Alzheimer's disease, and 23 with moderate Alzheimer's disease. Forty-five images were used to determine the type of naming errors, and to identify the underlying cause of errors, matching an image with a written word was used. Results: Patients with Alzheimer's disease had more naming errors compared with the group of healthy elderly, and patients with moderate Alzheimer's disease showed a slower reaction in matching an image with a written word. Conclusion: Anomia in the initial phase of Alzheimer's disease is due to problems in lexical retrieval; however, as the disease advances, in addition to lexical retrieval problems, conceptual knowledge causes naming problems. (c) 2017 The Author(s) Published by S. Karger AG, Basel.
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