Journal
DENTAL MATERIALS JOURNAL
Volume 36, Issue 6, Pages 784-790Publisher
JAPANESE SOC DENTAL MATERIALS DEVICES
DOI: 10.4012/dmj.2016-321
Keywords
Mouthguard; Surface pre-reacted glass-ionomer filler; Physical property; Streptococcus mutans; Porphyronionas gingivalis
Funding
- JSPS KAKENHI [24592910]
- Grants-in-Aid for Scientific Research [16K20451, 24592910] Funding Source: KAKEN
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We developed an ethylene vinyl acetate (EVA) containing surface pre-reacted glass-ionomer (S-PRG) filler, as a new mouthguard material for preventing intraoral bacterial infection. We examined its physical properties, antimicrobial activity against a major cariogenic bacterium Streptococcus mutans and a periodontopathogen Porphyromonas gingivalis, and its cytotoxicity toward human gingival epithelial cells. S-PRG filler was added to EVA copolymer at 5, 10, 20, or 40 wt% and was processed into disc-shaped test specimens. Only minor differences between the Shore hardness and rebound resilience properties of EVA materials with and without the S-PRG filler were observed. The specimens with S-PRG filler showed bacteriostatic activity toward S. mutans and P. gingivalis and inhibited S. mutans biofilm formation. No cytotoxicity against the gingival epithelial cells was observed. Our findings show that EVA containing S-PRG filler has antimicrobial activity toward pathogenic oral bacteria and may be an effective material for maintaining the oral health of athletes.
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