Journal
SUPRAMOLECULAR CHEMISTRY
Volume 30, Issue 5-6, Pages 430-437Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10610278.2017.1406603
Keywords
Peptides; artificial beta barrels; fullerene; encapsulation
Categories
Funding
- Ministerstwo Nauki i Szkolnictwa Wyzszego [0206/DIA/2016/45]
- Narodowe Centrum Nauki [2016/20/W/ST5/00478]
Ask authors/readers for more resources
A strategy that utilizes macrocyclic resorcin[4]arenes for the pre-positioning of peptides to form cavitands that subsequently self-assemble through hydrogen bonds was used for the formation of molecular capsules. Hydrophobic tri- and tetrapeptides were attached via their C-termini to tetraformylresorcin[4]arene using acylhydrazone linkers. The resulting cavitands self-assemble in relatively non-polar environments (chloroform or chloroform-methanol) forming non-covalent dimers through hydrogen bonding motifs resembling beta-sheets. NMR studies (ROESY and DOSY) indicate that the binding motif involves C-terminal amino acids from the peptide strands, while the N-terminal parts are positioned outside of the cavity. The capsules possess stable porous structures and they are able to quantitatively complex fullerenes C-60 and C-70. [GRAPHICS] .
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available