Journal
CNS SPECTRUMS
Volume 22, Issue -, Pages 39-48Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S1092852917000876
Keywords
ALKS-5461; esketamine; investigational antidepressants; ketamine; rapastinel; treatment-resistant depression; therapies
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Funding
- Alkermes
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There is a great unmet need for new medications with novel mechanisms of action that can effectively treat patients who do not benefit from standard antidepressant therapies. After a period in which it seemed as if the pharmaceutical pipeline for new antidepressants was going dry, the past decade has witnessed renewed interest, beginning with discovery of the antidepressant effects of ketamine. This article briefly highlights more recent research on ketamine and other investigational antidepressants.
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