A new 2-(2′-hydroxyphenyl)quinazolin-4(3H)-one derived acylhydrazone for fluorescence recognition of Al3+

A new 2-(2'-hydroxyphenyl)quinazolin-4(3H)-one derived acylhydrazone (QP) was designed and synthesized as a fluorescent sensor. In Tris center dot HCl buffer (10 mM, pH 7.4)/ethanol (1/9, v/v) solution, QP exhibits a highly selective fluorescence response to Al3+ over other metal ions with a significant blue-shifted and enhanced emission at 473 nm. QP interacts with Al3+ reversibly through a 1:2 binding ratio with a detection limit of 4.79 x 10(-8) M. Potential applicability of QP for Al3+ detection in tap and lake water samples were also examined by 'proof-of-concept' experiments. (C) 2016 Elsevier B.V. All rights reserved.