Co-metal-organic-frameworks with pure uniform crystal morphology prepared via Co2+ exchange-mediated transformation from Zn-metallogels for luminol catalysed chemiluminescence

Cation exchange-mediated transformation from Zn-metallogels (MOGs), which was a mild facile strategy relative to the demanding hydrothermal method, was employed to develop Co2+ metal-organic frameworks (Co-MOFs) at room temperature. The obtained Co-MOFs was of uniform octahedral morphology and possessed high activity to catalyze luminol chemiluminescence without extra oxidants. By adding cysteine, the CL emission of luminol-Co-MOFs system was further enhanced. Based on this phenomenon, Co-MOFs was utilized to build a practical sensing platform for cysteine determination. Under the optimized conditions, the relative CL intensity (Delta I) was proportional to the concentration of cysteine in the range of 2-10 mu M, and the detection limit was 0.49 mu M (3S/N). Moreover, the established method was applied to the determination of cysteine in commercially available pharmaceutical injections. (C) 2016 Elsevier B.V. All rights reserved.