Journal
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
Volume 40, Issue 3, Pages 704-707Publisher
ELSEVIER
DOI: 10.1016/j.etap.2015.09.001
Keywords
Danio rerio; Osmoregulation; Cortisol; Homeostasis; Psychotropic drug; SSRI
Funding
- CNPq [301992/2014-2, 301156/2012-3]
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The presence of fluoxetine in aquatic environments has been reported for decades. Here, we investigate the effects of exposure to fluoxetine on the stress response and osmoregulation in zebrafish. We show that stress response alters osmoregulation and that fluoxetine inhibits these stress-related changes in osmoregulation. The results suggest that the presence of fluoxetine in aquatic ecosystems can cause changes in response to stress and osmoregulation in fish. (C) 2015 Elsevier B.V. All rights reserved.
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