Journal
2017 39TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)
Volume -, Issue -, Pages 580-583Publisher
IEEE
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Funding
- NIH [R01 DE023816]
- Strategic Young Researcher Overseas Visits Program for Accelerating Brain Circulation, JSPS, JAPAN
- National Center for Advancing Translational Sciences of the National Institutes of Health [UL1 TR000430]
- Mizzou advantage funding
- Div Of Biological Infrastructure
- Direct For Biological Sciences [1338066] Funding Source: National Science Foundation
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Feeding is a highly complex, essential behavior for survival in all species. Characterization of feeding behaviors has implications in basic science and translational medicine. We have been developing methods to study feeding behaviors using high speed videofluoroscopy (XROMM) in rats while self-feeding radiopaque flavored kibble. The rat is a popular model in translational medicine; however, it has not been studied using this methodology. Towards this goal, we surgically implanted radiopaque fiducial markers into the skull, mandible, and tongue of rats to enable motion tracking. We are developing computer vision tools to extract kinematics and behavioral features from XROMM videos to overcome barriers of current analysis methods. By understanding feeding dynamics, we will gain basic scientific knowledge and translational insights for feeding disorders caused by neurological conditions such as ALS, Parkinson's disease, and stroke.
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