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Foodborne mycotoxicoses, risk assessment and underestimated hazard of masked mycotoxins and joint mycotoxin effects or interaction

Journal

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
Volume 39, Issue 2, Pages 794-809

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.etap.2015.01.022

Keywords

Food safety; Human hazard; Risk assessment; Masked mycotoxins; Mycotoxin interaction; Foodborne mycotoxicoses

Funding

  1. European Community [PIRSES-GA-2012-316067]
  2. Department of Science and Technology in South Africa
  3. UK Royal Society Joint Project with Central and Eastern Europe
  4. Foundation of Ministry of Science and Education of Bulgaria

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The existing hazard of joint mycotoxin exposure of animals/humans and the significance of masked mycotoxins in foods or feeds and their respective contributions to the development of some food born mycotoxicoses is briefly reviewed. The importance of joint mycotoxin interaction in the complex etiology of some foodborn mycotoxicoses is covered in depth. The toxicity of low contamination levels of some combinations of mycotoxins ingested often by farm animals was carefully studied. The appropriate hygiene control and the necessary risk assessment in regard to mycotoxin contamination of foods and feeds are briefly analyzed and some useful prophylactic measures and management of the risk of mycotoxin contamination, in addition to tolerable daily intakes are also described. A reference is also made to the most suitable methods of veterinary hygiene control in some practical situations in order to prevent mycotoxins contaminating commercial food commodities and endangering public health. (C) 2015 Elsevier B.V. All rights reserved.

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